FGF12 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019795
Fusion event
HBV-FGF12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1800
Integrated sequence
AGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGT| |CTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGG
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
GRCh37.55
Start
192280418/192562629 (Hg38)
End
192280418/192562629 (Hg38)
Location type
Intron4
Target gene
FGF12
miRNAs that regulate target gene
hsa-mir-4668-5p ; hsa-mir-3613-3p ; hsa-mir-590-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-let-7g/Upstream/2732620; hsa-mir-3137/Downstream/2571877;
Nearest TSS
ENST00000440867/Upstream/45798; ENST00000264735/Downstream/164871;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/47281, chr3-CpG: 116/Downstream/353891
Upstream sequence
CAAAAAACAAAATAAACAAACAAACAACCTGATTAACTGGCACTGAGCTAAACAAGAAAGCTCCTGGCAGCAAGTGAAGAAACACCCTGTTGGCTCTAAA
Downstream sequence
AAACATATTTGTAATCAGTAAATAGGTATACTCTTCATTATGGCAACTAGTATGGAAATTTGGGTACAGAAGATAAATTCTGGGTGATACTAACCCTACC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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