CYP2J2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019800
Fusion event
HBV-CYP2J2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1818
Integrated sequence
GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT
Host Sequence
Chromosome
chr1
Cytoband
p32.1
Reference genome
GRCh37.55
Start
60386815/59921143 (Hg38)
End
60386815/59921143 (Hg38)
Location type
Intron8
Fragile sites / regions
FRA1B
Target gene
CYP2J2
miRNAs that regulate target gene
hsa-let-7b-5p
Nearest miRNA
hsa-mir-12136/Upstream/187847; hsa-mir-101-1/Downstream/1924932;
Nearest TSS
ENST00000473358/Upstream/7905; ENST00000456878/Downstream/5612;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/105767, chr1-CpG: 24/Downstream/5457
Upstream sequence
CTCTGGCCACCCCCACAGCCACGGCTCCCACTGCCAGCACCAGGCCCAGGGGCACCAGGGTGGAGACCAGCGCTCTGGAGCTTCCACCTTGTTCCTCAGA
Downstream sequence
GCTGGAAGAAGGCTTAAGTTAGTTCATCCCTGGAAGGGAGATCTGGGGGCCCGACGATGTGCTGGCAAGGTTGGCTTAGTCCTTTTTCCTCCCAGGTTTA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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