Basic Information
VIS ID
TVIS10019802
Fusion event
HBV-LOC284950 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1724
Integrated sequence
AACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGT| |TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37.55
Start
86044296/85817173 (Hg38)
End
86044296/85817173 (Hg38)
Location type
Intron1
Fragile sites / regions
FRA2S ; FRA2L
Target gene
LOC284950
Nearest miRNA
hsa-mir-1285-2/Upstream/33496; hsa-mir-10b/Downstream/375853;
Nearest TSS
ENST00000437798/Upstream/2043; ENST00000455121/Downstream/29080;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/44667, chr2-CpG: 104/Downstream/71294
Upstream sequence
CTCGATATCCAGTGAGCTGAACATTGGGTGGTGTCCACTGGGCGCTCAGGCTTGTGGGTGTGACCTGAGTGAACTTCAGGTCAGTTGGTGCAGGAATAGC
Downstream sequence
TTCCATTACTAATGAgaagcactgggaggttagtaacttgctcgaggccctgcgtctaggaagttggactggagcttggctctttgactccagaggctgc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate