Basic Information
VIS ID
TVIS10019812
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1817
Integrated sequence
TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT| |GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCT
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37.55
Start
18392779/18239845 (Hg38)
End
18392779/18239845 (Hg38)
Nearest miRNA
hsa-mir-1244-3/Upstream/566451; hsa-let-7i/Downstream/5972576;
Nearest TSS
ENST00000382841/Upstream/37775; ENST00000536967/Downstream/7769;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/2328245, chr12-CpG: 131/Downstream/889546
Nearby gene
PIK3C2G
Upstream sequence
gtaactggaagaaatcagagtatgggaggcaaaagagatcaggctatttatttctccatccctatacttttcctgctttgctacaattctagctgattct
Downstream sequence
TAAGTAGACATTGTCTTGGCAAAAGTACAGAActttgagccagcagcaaacttctagaaatttatcctacagataactatactcccaaatagataaaatg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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