Basic Information
VIS ID
TVIS10019814
Fusion event
HBV-IGH integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1645
Integrated sequence
ACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCC| |AAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGG
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37.55
Start
107267785/106859570 (Hg38)
End
107267807/106859592 (Hg38)
Location type
Intronic
Target gene
IGH
Nearest miRNA
hsa-mir-1185-1/Upstream/8571;
Nearest TSS
ENST00000550708/Upstream/8153; ENST00000521105/Downstream/6303;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/46496, None/Downstream
Nearby gene
MIR5195
Upstream sequence
cctcagttttttcatcacacctgaaattttttgcctctagttccagctgttgtggcctaatactaaaatgttttatcttcaaagtctaaaaaagcaatgt
Downstream sequence
gtttatagagtttacccccagagatcatctttgtcctattgcatgcatgtgttacaaaatactgaaagtgattcctgtgtgatatccactccaatcatga
Target sequence
ttggcagctaaaaggcccatac
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate