Basic Information
VIS ID
TVIS10019815
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1655
Integrated sequence
TGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTAC| |ATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGAT
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37.55
Start
107281215/106873005 (Hg38)
End
107281215/106873005 (Hg38)
Location type
Intronic
Target gene
IGH ; IGHV4-80
Nearest miRNA
hsa-mir-1185-1/Upstream/22006;
Nearest TSS
ENST00000550708/Upstream/4913; ENST00000640749/Downstream/181;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/59931, None/Downstream
Nearby gene
MIR5195
Upstream sequence
tctttaataaaatgtaaaactcccttggccaaaggttctcccactagcactatggaatcatgttccactcctcagggtgcatcagttattaccctatgac
Downstream sequence
GCTTCACCAGTCCTGGGCCCCACTCCTGCAGCTGCACTGGGACAGGACCCCTGTGAACACAGAGACCCACTGTGAGCCCTGGGCTCAGATGCAGCCTCCC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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