Basic Information
VIS ID
TVIS10019823
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr3
Cytoband
q11.2
Reference genome
GRCh37.55
Start
97853999/98135155 (Hg38)
End
97854283/98135439 (Hg38)
Nearest miRNA
hsa-let-7g/Upstream/1775116; hsa-mir-12124/Downstream/1828875;
Nearest TSS
ENST00000440867/Upstream/2457; ENST00000437310/Downstream/12040;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/162590, chr3-CpG: 57/Downstream/387126
Nearby gene
OR5H1
Upstream sequence
ctacaactctacaaaaatatacaaaaaattagccaggcacatgcctatagtcccagttactcatgaggctgaggtggaagggtcacttaagcctaggaag
Downstream sequence
tctcattatgggatattgactaaaactcaggcatacttgcactctctgtggccagcacagctggtttgtctttgtctcagcatggaactcataagttaca
Target sequence
gaaggtgcaagagaggagataaaggcttttacagggcaaatgtgaaagtatggcaaaagtaaagattgtattggttaaagtggagcagtagtgttattttgatcattccagtggaaaattcctagttagaaattagctggggtttttggttggttaaagttaacttttgttttaccatttacaatgagttggattcctgtttgcttaggtacaaacccactttgctggacccacgtcagcctgatatacttttat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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