Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019828
Fusion event
HBV-DCAF5 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1801
Integrated sequence
GGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC| |TGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGG
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
Start
End
69617084/69150367 (Hg38)
Location type
Intron8
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-218-5p ; hsa-mir-653-5p ; hsa-mir-1261 ; hsa-mir-7515 ; hsa-mir-5191 ; hsa-mir-4781-3p ; hsa-mir-3154 ; hsa-mir-409-3p ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6826-3p ; hsa-mir-6756-3p ; hsa-mir-3127-3p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p
Nearest miRNA
hsa-mir-208a/Upstream/1708437; hsa-mir-1185-1/Downstream/3366453;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/170258, chr14-CpG: 163/Downstream/1252
Upstream sequence
ATTCCAGCCCCTTCCCTGGGGACTGGCGGACCAGCTCCACCAGTTACCACTGCTGATGGAGTCACCAGAGACAGCGCATGTGAGGGACAGGGTCTCCGAA
Downstream sequence
CTCCTCTGTGGAAATGACCCTCCTCTTTCACAGGCTAAAATTAAGATAAAGGAAATGACCTGGCCAAGACTAGAGAAAATAGAGTTCATTTAAGATACAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.