KCNT2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019836
Fusion event
HBV-KCNT2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1727
Integrated sequence
GCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTA| |AAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37.55
Start
196531183/196562053 (Hg38)
End
196531183/196562053 (Hg38)
Location type
Intron27
Fragile sites / regions
FRA1K
Target gene
KCNT2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-4775 ; hsa-mir-500a-5p
Nearest miRNA
hsa-mir-101-1/Upstream/3425470; hsa-mir-1182/Downstream/20360;
Nearest TSS
ENST00000473358/Upstream/96666; ENST00000496761/Downstream/46306;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/3439959, chr1-CpG: 24/Downstream/46525
Upstream sequence
taagagtggaatcacatgatatttttccttttatgtctgtcaaattttatttagcatgctgttatcactatcattcctgctgtagtgtgtatcagaactt
Downstream sequence
cattctttttacgactgaataatattccattgtctgtataccacattttgtgaacccattcatctgttgatggacacttgggctcttcaacctggtaact
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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