NUP153 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019840
Fusion event
HBV-NUP153 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1605
Integrated sequence
CCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACG| |TCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCA
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37.55
Start
17676287/17676056 (Hg38)
End
17676287/17676056 (Hg38)
Location type
Intron20
Target gene
NUP153
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-26b-5p ; hsa-mir-744-5p ; hsa-mir-106b-3p ; hsa-mir-330-3p ; hsa-mir-93-5p ; hsa-mir-23a-3p ; hsa-let-7b-5p ; hsa-mir-4696 ; hsa-mir-125a-3p ; hsa-mir-6888-5p ; hsa-mir-4524b-3p ; hsa-mir-552-3p ; hsa-mir-5680
Nearest miRNA
hsa-mir-3691/Upstream/1534432; hsa-mir-10398/Downstream/895728;
Nearest TSS
ENST00000381078/Upstream/75701; ENST00000606771/Downstream/30201;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/74890, chr6-CpG: 117/Downstream/30005
Upstream sequence
taataaatggtgctgggaaaactggctagccatatgtagaaagctgaaactggatccgttccttacaccttatacaaaaattaattcacgtggattaaag
Downstream sequence
TTTTTTGATGGTGTATTTTGTAATACAGAAAGTAACTTCTGCCTTATAGTCCTATCATTCTGAGACCATAAAAAATAAGTTTTACCCGTATTTTGATACT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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