Basic Information
VIS ID
TVIS10019848
Fusion event
HBV-LINC02496 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1826
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37.55
Start
61644518/60778800 (Hg38)
End
61644549/60778831 (Hg38)
Location type
Intronic
Target gene
LINC02496
Nearest miRNA
hsa-mir-12113/Upstream/8066053; hsa-mir-1243/Downstream/143788;
Nearest TSS
ENST00000502981/Upstream/28214; ENST00000506379/Downstream/364825;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/3582851, chr4-CpG: 222/Downstream/421334
Nearby gene
MIR548AG1
Upstream sequence
CAGGGATGAGAATCAAAGATGCAAAGACCTAGCTGAAATGATCCCACTTGACCTATTTGGTGACATCAGAACTTCTGGAGCTCAAGAGAGAAGTGCTGAA
Downstream sequence
GAAAAATATCAGATTGATGGTAAATTATAAATTATACCTTTGATCAATGTAGAATATATGTGTTTATATAATCAGAAGTGACTACATCTATACATGCCTG
Target sequence
AAAGAGTCCACATTGCAAGTAATAATTTAGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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