Basic Information
VIS ID
TVIS10019853
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1824
Integrated sequence
TTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTT| |TTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAG
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37.55
Start
85035917/84642138 (Hg38)
End
85035917/84642138 (Hg38)
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/3483677; hsa-mir-1178/Downstream/2102930;
Nearest TSS
ENST00000382841/Upstream/357747; ENST00000393212/Downstream/225695;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1954271, chr12-CpG: 17/Downstream/269283
Nearby gene
SLC6A15
Upstream sequence
gtacttgttgaacaaaggaatAAAGCAGAGGACACATAAATAAAATCTATGATTTTCTTCTTCATTCTCAGAGCATACTTTCCTTCTTATCTCATAGATG
Downstream sequence
ggccaatatggtgaaacacctctctactataaatacaaaaattagccaggcatggtggcacaggcctgtagtcccagctactcgagaggccgaggcaaaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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