Basic Information
VIS ID
TVIS10019855
Fusion event
HBV-NATD1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1749
Integrated sequence
TCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGA| |GGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTT
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37.55
Start
21147448/21244135 (Hg38)
End
21147448/21244135 (Hg38)
Location type
Exon2
Target gene
NATD1
Nearest miRNA
hsa-mir-1180/Upstream/1899561; hsa-mir-10226/Downstream/6049775;
Nearest TSS
ENST00000595228/Upstream/29511; ENST00000534743/Downstream/9275;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/29417, chr17-CpG: 102/Downstream/8760
Upstream sequence
GGCCCACAGGAGAGGCACTGCACCTCTCAACTAGACAGAGCTGGCAAGTcgcggtggctcacacctgtaatcccagcactttgggaggctgaggctggcc
Downstream sequence
ACGGTAGGCATCTGGGACCTCGGTGTGCTGCAGGTCCACGATCCGCTTGCCCACGTACTCATAGAGCAGGACGGCCCGGTCATGACATCCTGGGGGTTGT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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