Basic Information
VIS ID
TVIS10019857
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1740
Integrated sequence
TGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGA| |GTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAA
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37.55
Start
66116879/65651196 (Hg38)
End
66116879/65651196 (Hg38)
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/592688; hsa-mir-11399/Downstream/977244;
Nearest TSS
ENST00000473358/Upstream/31256; ENST00000646875/Downstream/52766;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/125068, chr1-CpG: 63/Downstream/141561
Nearby gene
LEPR
Upstream sequence
acagcatgatgctgaggtttggggtagagatcctgtcatccagagagtgagcataggacccaataagtggcttattaacccacacttccctcctagcctc
Downstream sequence
cttcctctagtagtccacagtgtctattgttcccataaagacaaaaaaaaatagacattgtttagctcccacttataagtgagaacaagtgatatttggt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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