Basic Information
VIS ID
TVIS10019863
Fusion event
HBV-LOC107985988 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1802
Integrated sequence
GCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCT| |GCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGC
Host Sequence
Chromosome
chr2
Cytoband
q36.1
Reference genome
GRCh37.55
Start
221872026/221007306 (Hg38)
End
221872026/221007306 (Hg38)
Location type
Intronic
Target gene
LOC107985988
Nearest miRNA
hsa-mir-10b/Upstream/1100741; hsa-mir-1244-1/Downstream/4003155;
Nearest TSS
ENST00000437798/Upstream/216228; ENST00000609776/Downstream/418234;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1379241, chr2-CpG: 260/Downstream/563704
Nearby gene
EPHA4
Upstream sequence
GACTGCCCTCAGACATTAAAATAAAAAACAAAACAATTCACAATGACAGATATTAATACGAATAGCTAACGTTTGTATGGTGTTTTACACTAATGCTCTC
Downstream sequence
ttttaagttattttcttggaaactttggctattatttccagtgagattaaagattactttgacgagtttattaagtttcaagaaagatcttttgggatat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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