Basic Information
VIS ID
TVIS10019870
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1586
Integrated sequence
TCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCAC| |TTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTC
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
GRCh37.55
Start
33902725/33934948 (Hg38)
End
33902725/33934948 (Hg38)
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-1236/Upstream/35748; hsa-mir-10398/Downstream/65024;
Nearest TSS
ENST00000381078/Upstream/23846; ENST00000478214/Downstream/121375;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/145719, chr6-CpG: 21/Downstream/93213
Nearby gene
MIR7159
Upstream sequence
catgaggaAAAATTGAGAACAGGGTAATACCTTCAGCCTACATGTGTTATAAAGTTCATGttttttatataatataacttataaataaGTGGTTCTTGAA
Downstream sequence
GCCACCTTCAAATCCCAGCCAGACACTATCAAGCAGGAAAAGAGCTACCAGAGACCACCTCTGAGGAGGAGTCAAGCTCAGCATCCAGGGGCAGCCGTGC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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