VISDB Viral Integration Site DataBase

VIS ID

TVIS10019873

Fusion event

HBV-FOXK1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1804

Integrated sequence

ATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGC| |GCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCAT

Chromosome

chr7

Cytoband

p22.1

Reference genome

Start

End

4785965/4746334 (Hg38)

Location type

Intron2

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-186-5p ; hsa-let-7b-5p ; hsa-mir-1229-3p ; hsa-mir-615-3p ; hsa-mir-149-5p ; hsa-mir-15b-5p ; hsa-mir-203a-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-630 ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548k ; hsa-mir-548l ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-3607-5p ; hsa-mir-3908 ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-4495 ; hsa-mir-4524a-5p ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-4524b-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-5589-3p ; hsa-mir-548av-5p ; hsa-mir-548ay-5p ; hsa-mir-6838-5p ; hsa-mir-8054 ; hsa-mir-548bb-5p ; hsa-mir-6758-3p ; hsa-mir-137 ; hsa-mir-503-5p ; hsa-mir-561-5p ; hsa-mir-5692c ; hsa-mir-5681b ; hsa-mir-5692a ; hsa-mir-5701 ; hsa-mir-5692b ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-944 ; hsa-mir-646 ; hsa-mir-218-5p ; hsa-mir-570-3p ; hsa-mir-4501 ; hsa-mir-1537-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-4253 ; hsa-mir-6862-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-127-5p ; hsa-mir-7843-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-6740-3p ; hsa-mir-1251-3p ; hsa-mir-103b ; hsa-mir-6830-5p ; hsa-mir-8485 ; hsa-mir-329-3p ; hsa-mir-362-3p ; hsa-mir-4713-5p ; hsa-mir-663b ; hsa-mir-7155-3p ; hsa-mir-3136-3p ; hsa-mir-6499-3p ; hsa-mir-17-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-5693 ; hsa-mir-4257 ; hsa-mir-3677-5p ; hsa-mir-4749-3p ; hsa-mir-7108-3p ; hsa-mir-6887-3p ; hsa-mir-4640-3p ; hsa-mir-3692-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-6890-3p ; hsa-mir-1199-3p ; hsa-mir-1252-5p ; hsa-mir-1324 ; hsa-mir-134-3p ; hsa-mir-140-3p ; hsa-mir-1908-3p ; hsa-mir-1914-3p ; hsa-mir-198 ; hsa-mir-2117 ; hsa-mir-22-3p ; hsa-mir-26b-3p ; hsa-mir-3160-3p ; hsa-mir-3177-3p ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3184-5p ; hsa-mir-3196 ; hsa-mir-340-3p ; hsa-mir-3609 ; hsa-mir-3648 ; hsa-mir-3650 ; hsa-mir-3657 ; hsa-mir-3665 ; hsa-mir-3688-3p ; hsa-mir-3689d ; hsa-mir-3714 ; hsa-mir-3934-5p ; hsa-mir-3978 ; hsa-mir-423-5p ; hsa-mir-425-3p ; hsa-mir-4269 ; hsa-mir-4273 ; hsa-mir-4279 ; hsa-mir-4285 ; hsa-mir-432-3p ; hsa-mir-4419a ; hsa-mir-4446-3p ; hsa-mir-4455 ; hsa-mir-4466 ; hsa-mir-4485-5p ; hsa-mir-4487 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4504 ; hsa-mir-4505 ; hsa-mir-4510 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4533 ; hsa-mir-4632-3p ; hsa-mir-4669 ; hsa-mir-4675 ; hsa-mir-4681 ; hsa-mir-4687-3p ; hsa-mir-4694-3p ; hsa-mir-4736 ; hsa-mir-4741 ; hsa-mir-4747-5p ; hsa-mir-4764-5p ; hsa-mir-497-3p ; hsa-mir-5001-5p ; hsa-mir-5194 ; hsa-mir-5196-5p ; hsa-mir-542-3p ; hsa-mir-548ah-5p ; hsa-mir-558 ; hsa-mir-5681a ; hsa-mir-5787 ; hsa-mir-605-3p ; hsa-mir-6078 ; hsa-mir-609 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6134 ; hsa-mir-651-3p ; hsa-mir-6715b-5p ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6741-5p ; hsa-mir-675-5p ; hsa-mir-6760-5p ; hsa-mir-6770-5p ; hsa-mir-6772-5p ; hsa-mir-6776-5p ; hsa-mir-6790-3p ; hsa-mir-6808-5p ; hsa-mir-6816-5p ; hsa-mir-6820-5p ; hsa-mir-6827-3p ; hsa-mir-6851-5p ; hsa-mir-6893-5p ; hsa-mir-7114-5p ; hsa-mir-7156-5p ; hsa-mir-762 ; hsa-mir-764 ; hsa-mir-940 ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-25-5p ; hsa-mir-30b-3p ; hsa-mir-3192-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-4459 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4728-5p ; hsa-mir-490-3p ; hsa-mir-5186 ; hsa-mir-6087 ; hsa-mir-6516-5p ; hsa-mir-658 ; hsa-mir-6724-5p ; hsa-mir-6773-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-7851-3p

Nearest miRNA

hsa-mir-339/Upstream/2219189; hsa-mir-10399/Downstream/42231;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/907, chr7-CpG: 18/Downstream/796

Upstream sequence

ttttaaaacctataaactctccttacaattcccccattttacctgtcctaaaaccagacaagtattacaggttagttcaggatctgcgccttatcaacca

Downstream sequence

TACGTTAGAAATACTCTCCTTTTTCTGACAACTTTGGTAGCTTCCTGCAGGGTGATTCATCTCTTTCAAAGTTTCTGGTTGGCTGGGTGTGGTGACgcac