Basic Information
VIS ID
TVIS10019875
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1773
Integrated sequence
TCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGT| |ACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCT
Host Sequence
Chromosome
chr8
Cytoband
p23.1
Reference genome
GRCh37.55
Start
9725539/9868029 (Hg38)
End
9725539/9868029 (Hg38)
Nearest miRNA
hsa-mir-3674/Upstream/126261; hsa-mir-10400/Downstream/35359;
Nearest TSS
ENST00000518652/Upstream/97898; ENST00000521209/Downstream/33171;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/311446, chr8-CpG: 60/Downstream/30638
Nearby gene
LINC00599
Upstream sequence
gaataatgctgcaatgaatattggcatacacgtatctgttttttgagtccttcctttcagttctttttggcatatactgaggaatgaagttgttgaatca
Downstream sequence
GAATATTAGACTGTTTTCTGAGCTCATCAACTTTAGGCAGCCAAAAAAGTTGGCTATATATTGGGCCCAATCAAGAGAAGTAATAGAAACATAAGATAAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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