Basic Information
VIS ID
TVIS10019877
Fusion event
HBV-LOC105378466 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1800
Integrated sequence
AGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGT| |CTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGG
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37.55
Start
107098698/105338940 (Hg38)
End
107098698/105338940 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LOC105378466
Nearest miRNA
hsa-mir-107/Upstream/1070535; hsa-mir-202/Downstream/5559150;
Nearest TSS
ENST00000439456/Upstream/180012; ENST00000424701/Downstream/480257;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/695886, chr10-CpG: 100/Downstream/1825082
Nearby gene
LINC02627
Upstream sequence
gagttcgagaccagcttaaataccatggagaaaccctgtctctactaaaaatacaaaaaaattagctgggtgtggtggcgcatacctgtaatcccagcta
Downstream sequence
GCAAAACCCAAAAGACCCAAAACAAAGAAAGCTAAATCAGATTCAAGGAAAAAATGACCTGGCACTGTGGGTTCACTTTTAAAAAGGCAAAAAGTCACTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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