Basic Information
VIS ID
TVIS10019884
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1545
Integrated sequence
AATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGG| |ACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCC
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
GRCh37.55
Start
40709058/43129093 (Hg38)
End
40709058/43129093 (Hg38)
Nearest miRNA
hsa-mir-1-2/Upstream/3452314; hsa-mir-122/Downstream/1840989;
Nearest TSS
ENST00000575820/Upstream/13402; ENST00000591940/Downstream/143058;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/3287228, chr18-CpG: 180/Downstream/1549925
Nearby gene
SYT4
Upstream sequence
CATCTATCTTATATGTATGCATGGTATTCTTTTTTTATGCAAAATTTTATGCTGGACCCTGTTCTGGCTGTACATAGTAAAGAATGTACTTGAGGTACTT
Downstream sequence
tttggtttatttgtaatttcttcccatttgttttagatttactgtgtgcagcaatagagaacaatcttcctcaaaaataaatatttaaatgattggcggc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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