Basic Information
VIS ID
TVIS10019885
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1439
Integrated sequence
CTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCG| |GCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTT
Host Sequence
Chromosome
chr18
Cytoband
q21.33
Reference genome
GRCh37.55
Start
60739013/63071780 (Hg38)
End
60739013/63071780 (Hg38)
Nearest miRNA
hsa-mir-1-2/Upstream/4620622; hsa-mir-5011/Downstream/4009804;
Nearest TSS
ENST00000575820/Upstream/165493; ENST00000634673/Downstream/90089;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/354642, chr18-CpG: 236/Downstream/246490
Nearby gene
BCL2
Nearest cancer related gene
BCL2(OG, No orient)
Upstream sequence
AAAATATAGCTGGTTGTTTTTAGTCTAAAATATGACACAAATGTATGGTATATGGTTTTGCTATTAATATTTTGAAAAGACTATAAtgtattgaaataaa
Downstream sequence
caacatataaatcttgtgggTTTAGTGAGGAAAATAAACACACAATCTAACCTTTCCTGGACTGCTTGCAGGAGCATCAAGTCCTCTTGCTCTTCCATCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate