Basic Information
VIS ID
TVIS10019886
Fusion event
HBV-IGL integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1806
Integrated sequence
ACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGC| |ACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG
Host Sequence
Chromosome
chr22
Cytoband
q11.22
Reference genome
GRCh37.55
Start
22733331/22378962 (Hg38)
End
22733340/22378971 (Hg38)
Location type
Intronic
Target gene
IGL
Nearest miRNA
hsa-mir-1286/Upstream/725577; hsa-let-7a-3/Downstream/443805;
Nearest TSS
ENST00000624155/Upstream/2976; ENST00000390297/Downstream/1795;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/155443, chr22-CpG: 69/Downstream/129334
Nearby gene
BMS1P20
Upstream sequence
CACACAGAGACTGGGGTTTTGGTCTGTCCCTGAGGGTCCCTCAGGAGGATCACATAAAAAATCCATAGTCAGTGTCCTCTGTCCAAGGCTCACTGTCCCA
Downstream sequence
CCTCCCGGATCCTCTGGGTGTCCACATCCTGTAGTTTTGGACCTGTTCTTCTCTCTGCCCTCAACCTAACAGCTGATGGGGCATCCACCAGGAAGCGCAT
Target sequence
GCTGTTGTC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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