DLG1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019891
Fusion event
HBV-DLG1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1818
Integrated sequence
GTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATG| |CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTT
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37.55
Start
196920492/197193621 (Hg38)
End
196920492/197193621 (Hg38)
Location type
Intron20
Target gene
DLG1
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-218-5p ; hsa-mir-9-3p
Nearest miRNA
hsa-let-7g/Upstream/1311226; hsa-mir-4797/Downstream/100257;
Nearest TSS
ENST00000440867/Upstream/9490; ENST00000414529/Downstream/32738;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/163118, chr3-CpG: 115/Downstream/103935
Nearest cancer related gene
DLG1(TSG, No orient, 0)
Upstream sequence
tcctaaagtgctgggattacagacatgagccaccatgcccagccAGAACTGTTTTTACATGAGAGAGCAGGTAACTGGCTAAGTGACCAATGTGAGGCAA
Downstream sequence
aaagagtgcaagttaaatatacagtatgagtccatttatataaagtccaaaatatgcaaaacaattgattagcaatcgaaatatatggtagaactttaat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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