Basic Information
VIS ID
TVIS10019894
Fusion event
HBV-LOC105370003 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1822
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chr12
Cytoband
q24.21
Reference genome
GRCh37.55
Start
116115759/115677954 (Hg38)
End
116115759/115677954 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12E ; FRA12C
Target gene
LOC105370003
Nearest miRNA
hsa-let-7i/Upstream/2386346; hsa-mir-1178/Downstream/470606;
Nearest TSS
ENST00000382841/Upstream/38220; ENST00000549163/Downstream/77308;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/225764, chr12-CpG: 46/Downstream/239028
Nearby gene
MED13L
Upstream sequence
TCACGcaccgggctgcttgcggctctggactattgtgaataaggccggtgtgagtattttactgtaagtctttggggacgtgtcttcatgccccttgggt
Downstream sequence
gaatccaggtgtgagattgccgggccGGGGTGCTGTGAGTTACCTTTGGTTATAGGGAGGTGGTGACCCATGGTGGCTCCAAGTGCCCGTGGCCTTTCGT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate