VISDB Viral Integration Site DataBase

VIS ID

TVIS10019896

Fusion event

HBV-TERT integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

459

Integrated sequence

TTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAA| |GGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATC

Chromosome

chr5

Cytoband

p15.33

Reference genome

Start

End

1268745/1268630 (Hg38)

Location type

Exon7

Target gene

miRNAs that regulate target gene

hsa-mir-138-5p ; hsa-mir-498 ; hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-512-5p ; hsa-mir-1207-5p ; hsa-mir-1266-5p ; hsa-mir-1182 ; hsa-mir-181a-5p ; hsa-mir-6776-3p ; hsa-mir-197-3p ; hsa-mir-6740-3p ; hsa-mir-6760-3p ; hsa-mir-532-5p ; hsa-mir-3064-5p ; hsa-mir-422a ; hsa-mir-346 ; hsa-mir-1226-3p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-143-3p ; hsa-mir-3161 ; hsa-mir-3605-5p ; hsa-mir-3620-3p ; hsa-mir-3682-3p ; hsa-mir-4323 ; hsa-mir-4712-3p ; hsa-mir-4733-3p ; hsa-mir-4758-3p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-7112-3p

Nearest miRNA

hsa-mir-4635/Upstream/205656; hsa-mir-10397/Downstream/40680;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/11523, chr5-CpG: 26/Downstream/2033

Nearest cancer related gene

TERT(OG, No orient, 0)

Upstream sequence

TCAGCCTAGCACTTACTGGCTTCATGCAGGATCTTGCCCAGTTCTCTGTACCTCAGAGAGCTTTTTCCTTCTTCCAAAGAAAGTGTCTTCATTACGTAAC

Downstream sequence

GACCTGGGGCGGGAAGACACAGGTGAGAGACGGGCAGGGCATGTGCTGGACATGCGTACACTCAAACCGAGCCACACACAGACACAGAACCTCATACACA