Basic Information
VIS ID
TVIS10019899
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1792
Integrated sequence
CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG
Host Sequence
Chromosome
chr4
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
69844132/68978414 (Hg38)
End
69844132/68978414 (Hg38)
Nearest miRNA
hsa-mir-12113/Upstream/2701486; hsa-mir-1243/Downstream/7595154;
Nearest TSS
ENST00000502981/Upstream/26623; ENST00000502942/Downstream/72949;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/628211, chr4-CpG: 55/Downstream/1709723
Nearby gene
UGT2B10
Upstream sequence
tctgcagcttgaagacagttttgcaaagaatgttgcaggtactcactattataaataaataaataaataaataaataaataaatagcacagaagttggag
Downstream sequence
AAACATGTATACATGTAGCTGACCAAATTTTGCCCAGAGGACCCAATTGATTTGTCAACCCTTGGTTAATTAAATTATAAGAAATTTAATTCTGACATAT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
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