Basic Information
VIS ID
TVIS10019903
Fusion event
HBV-chr13 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr13
Cytoband
q33.2
Reference genome
GRCh37.55
Start
106702489/106050140 (Hg38)
End
106702512/106050163 (Hg38)
Nearest miRNA
hsa-mir-1297/Upstream/4004136; hsa-mir-1267/Downstream/1481008;
Nearest TSS
ENST00000623511/Upstream/359711; ENST00000643760/Downstream/324314;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/3203727, chr13-CpG: 29/Downstream/442897
Nearby gene
LINC00460
Upstream sequence
acagagttccaggacttactttgagcttctgattcacagatctggggtgggccacagaacatgcatttctaacaagttcccaggtgaccctggtgcactg
Downstream sequence
tgaagcttaaggaagagataaaagccacagagctacagagcaaatttggaaaccatcatcaatctgttgatatcaacacagttctcagactggacaagac
Target sequence
TCTTACaggtagtgataaagcag
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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