VISDB Viral Integration Site DataBase

VIS ID

TVIS10019906

Fusion event

HBV-CDK15 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

457

Integrated sequence

ACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATC| |AAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTA

Chromosome

chr2

Cytoband

q33.1

Reference genome

Start

End

202755505/201890782 (Hg38)

Location type

Intron12

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-6867-5p ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6782-5p ; hsa-mir-876-3p ; hsa-mir-323a-5p

Nearest miRNA

hsa-mir-10b/Upstream/12757670; hsa-mir-1244-1/Downstream/4892452;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/109349, chr2-CpG: 334/Downstream/141881

Upstream sequence

ACGTGCACCTCATCATGTGACCCATGTCATGCTGCTTATCCCACTGATCTCCAATGCGGTACATGACCCCTTCATTGGTTGTGCAGATTTCCTCGTGGGC

Downstream sequence

AGAGGAGTCTTTGTTTACAGTTTCAGGAGTGAGGCTAAAGCCAGAAATGTGTGACCTTTTGGCCTCCTACCAGAAAGGTCACCACCCAGCCCAGTTTAGC

Target sequence

C