Basic Information
VIS ID
TVIS10019907
Fusion event
HBV-chr20 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1757
Integrated sequence
AAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTA| |GGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGT
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
19160600/19179956 (Hg38)
End
19160600/19179956 (Hg38)
Fragile sites / regions
FRA20A
Nearest miRNA
hsa-mir-103a-2/Upstream/709265; hsa-mir-1-1/Downstream/7028230;
Nearest TSS
ENST00000382410/Upstream/123160; ENST00000613834/Downstream/32690;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/591508, chr20-CpG: 155/Downstream/31859
Nearby gene
SLC24A3
Upstream sequence
aaaaagagatcttactgtattgcccaggctggtcttgaactcctgggctcaagggatcctcctgcctcggcctcccaaagtgctgggattacaggtgtga
Downstream sequence
AGTTAAGAATCCTATGTGAAAAGTTTCTTCTAAAAATGTGACAAGGGTATTTTACTGAATTCTACAATGCTATACTCAAAAAGGGTAATAATCTTACTTA
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate