Basic Information
VIS ID
TVIS10019910
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1812
Integrated sequence
AAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGC| |ACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCG
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
87553673/87842781 (Hg38)
End
87553673/87842781 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA11F
Target gene
LOC107984361 ; RAB38
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-let-7b-5p ; hsa-mir-30a-5p
Nearest miRNA
hsa-mir-10392/Upstream/1564383; hsa-let-7a-2/Downstream/333721;
Nearest TSS
ENST00000527297/Upstream/123370; ENST00000532849/Downstream/207325;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/804730, chr11-CpG: 45/Downstream/332294
Nearby gene
LINC02711
Upstream sequence
TCATATTGTACATCATATTAAAAAATCAACTTTGGAAGGGGGAACACATCTAACCCAGCATTATTGTTCAATATTGGAATTGCATGCAAATCAAATGAAA
Downstream sequence
TTGTATCTGTGAAGGGCGGCTGtttttctttcttttttttttgatggagtctcgccctgttgcccacgctggagtgcagtggcacaatcttggctcactg
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
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