Basic Information
VIS ID
TVIS10019918
Fusion event
HBV-chr19 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1787
Integrated sequence
ACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTA| |GGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTT
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
33761715/33270809 (Hg38)
End
33761715/33270809 (Hg38)
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-mir-10395/Upstream/12871455; hsa-let-7e/Downstream/1851891;
Nearest TSS
ENST00000633603/Upstream/44959; ENST00000589932/Downstream/14930;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/34615, chr19-CpG: 302/Downstream/30346
Nearby gene
CEBPA
Nearest cancer related gene
CEBPA(TSG, No orient)
Upstream sequence
catcgtctctatctccagaagaggcccagaatctaaccacttctctccacttccactgtctccattctgctccgagctaccgttactcctcacctgcatc
Downstream sequence
ccctgctccttcctcctggataatttctgcttatattttaagacttagcttccagatgtggcggttcatgcctgtaatcccagaattttgggaggctgca
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate