Basic Information
VIS ID
TVIS10019920
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27064257
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1785
Integrated sequence
CAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTG| |TAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCC
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
71198428/71733443 (Hg38)
End
71198436/71733451 (Hg38)
Fragile sites / regions
FRA7J
Nearest miRNA
hsa-mir-1183/Upstream/425673; hsa-mir-10399/Downstream/964452;
Nearest TSS
ENST00000635602/Upstream/397894; ENST00000434423/Downstream/77044;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/600047, chr7-CpG: 187/Downstream/602321
Nearby gene
CALN1
Upstream sequence
AAAAATGTATAAGCTTTGGCTGAAGGGCAAGACTGGTCATAAAAAATAAACCTATCTCCCCTATTCAAACACCAGATGAAGCAAAGATTTTTCTTTTTTT
Downstream sequence
AGCGCCCCCTGCTGGCGCCTGGCCTTGATTCCGCTGCTTCCTTTCCCCTGAAATGAAGGAAAGCAGGAGGGTTGTGAGGCTTCATTGATTTCTCCCCGGC
Target sequence
GATGCTCT
Reference
Fujimoto, A., et al. Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. Nat Genet ,2016,48(5): 500-509.
Curate