VISDB Viral Integration Site DataBase

VIS ID

TVIS10019930

Fusion event

HBV-KCNH1 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2013

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr1

Cytoband

q32.2

Reference genome

Start

End

211059193/210885851 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-296-3p ; hsa-mir-335-5p ; hsa-mir-34a-5p ; hsa-mir-7704 ; hsa-mir-615-5p ; hsa-mir-2467-3p ; hsa-mir-4257 ; hsa-mir-6890-5p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6753-5p ; hsa-mir-1911-3p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-505-3p ; hsa-mir-4290 ; hsa-mir-1233-3p ; hsa-mir-7113-3p ; hsa-mir-4673 ; hsa-mir-339-5p ; hsa-mir-4645-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-4687-5p ; hsa-mir-508-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1261858; hsa-mir-1182/Downstream/1191762;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/201448, chr1-CpG: 92/Downstream/247474

Upstream sequence

TTCCATTCAGTGATCCAATCTCCTTATATCTCATTTGGTTACCAAGAGTGTACAGTATACATTTAgtcatatacagccttgtattttgcctggcatatga

Downstream sequence

tctctgggcagaccatgtctgaaagagaggcagcagccccagtcagggtcttatagataaaactcccatatccctgggacagagcacctgagggaaatgg

Target sequence

actctggccaaaatactatgcttttcccacagtcttcacaacctgcagaccaagagattccctcaggtgcctataccaccagggccctgggtttcaagcacaaaaccgggctgccatttgggcaggagttttttttttcataccccagtggcacctggaacaccagcgagacagaaccattcactcccctgggaagggggctgaagccagggagccaagtggtctagttcagtggatcccacctcaatggacccc