Basic Information
VIS ID
TVIS10019931
Fusion event
HBV-LOC105375228 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr7
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
35111020/35071408 (Hg38)
End
35111311/35071699 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7C
Target gene
LOC105375228
Nearest miRNA
hsa-mir-1183/Upstream/130574; hsa-mir-10399/Downstream/1847658;
Nearest TSS
ENST00000635602/Upstream/33137; ENST00000605778/Downstream/181932;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/33212, chr7-CpG: 97/Downstream/114052
Upstream sequence
GCTTTATGTAGGGAAAGCTCCAAATGCTAGAGAAAGCTTAATATGGTAAAGCACATGTGTAACTCCACAATGTGCAAATTCCAAATCACCAAGTAACATT
Downstream sequence
TCATCTACCCAACCACCACTTATGTCCTTTTCCCTCCACATCCCTCTTCTTTCAAAATCCCTCCCCTCCTACTCACCTTCTTCAGGTAGCAGGAGTGGGA
Target sequence
acttatctgcaaatcaagaggaaagatcccagaagatactaaccctcctgatagataccttgatctccgacacctgtctgtggtacttgatgatggcaccctagcaaactaacataATTGTGATGAAACACAGAGGCCCAAGAGTGGCCTTTGTGTTTCATTTCAGTGCTCTATGTTCTGGCCAATTGTCTGTCATCTTCCTTTGTGCGTGAATGAGTCCCCTGTGGGCAAAAGCAGAGGCCACCCGTGGAGACA
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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