VISDB Viral Integration Site DataBase

VIS ID

TVIS10019940

Fusion event

HBV-PPWD1 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2013

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr5

Cytoband

q12.3

Reference genome

Start

End

64878637/65582810 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-361-3p ; hsa-mir-7153-5p ; hsa-mir-7641 ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-589-5p ; hsa-mir-4502 ; hsa-mir-4699-3p ; hsa-mir-4773 ; hsa-mir-4662a-5p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-8066 ; hsa-mir-6768-3p ; hsa-mir-606 ; hsa-mir-340-5p ; hsa-mir-4423-3p ; hsa-mir-4775 ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-3622a-5p ; hsa-mir-5582-5p ; hsa-mir-32-3p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-6875-3p ; hsa-mir-6883-3p ; hsa-mir-630 ; hsa-mir-4999-5p

Nearest miRNA

hsa-mir-10397/Upstream/5878876; hsa-mir-103a-1/Downstream/6586657;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/19123, chr5-CpG: 30/Downstream/41277

Upstream sequence

CTGGTTCAGTCCTATGTTTTCTTTTGCCTTGAAAATAGTGTTAAGGTAAATTTCAAATCATGAAAAACATAGGAAATTATAACTATGTGAAATAAATCGC

Downstream sequence

TTGAAATCAATGTGTTCAGTATGTTATGTGGATCCTTTTCATATTAGACAATGTAAAAATAATTTAATTGCCTGACACATCCTGTATGGGAAGTGATTCC

Target sequence

tgtactgttatcatcatatatgagtgagggaagagaagaaatgaattcacatccccaaagtcgcagaactggaattcaaatccaaacaatctAAATAATGAACTGAGCAACAAACAGGTGGCATGTTAGGCCTTACTAGAAGGCATAAGTCGAGAGCTACCACAAATGAAACAATTATTCTTGTTAAATGTTTGCCCAAGAAAATTTCTAACCAAAGAAATTAAATTCCAT