PRPF31 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019941
Fusion event
HBV-PRPF31 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
70196260/70162357 (Hg38)
End
70196416/70162513 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
PRPF31
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1225/Upstream/131935; hsa-mir-11401/Downstream/6706423;
Nearest TSS
ENST00000527434/Upstream/16553; ENST00000565806/Downstream/10809;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/47501, chr16-CpG: 69/Downstream/25534
Upstream sequence
CCTTAGACTTGGCAGACTTCTCATTCTTACAGGGCACCCCCTTCGTTGGCGTTCTGTTAGGAAGAGACCCACAGGCAGCACCCCCCTCAGTAGTGCTTCC
Downstream sequence
AAACACATTTTAACTACTCTTGCACGGCTGCTTGTGAAATGTTCTTCATCTGTAGTGACTTAAATGTGTTTGCCACCACAAAGCATAAACAGCGTGCAGA
Target sequence
AAGTGGGATCTTTTCTAGAGATCCTGGGTGACTTTGGGTGCACAGGGTGACCGAGCATTTCTGCCCCTGTGAATGTGGCACTAACACTGTGCACTGTCTCCACCAAGCAAGGTTTCCACTGAGTTTCTTCTCATGTTACTGGGTTTGTAAATGAAT
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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