Basic Information
VIS ID
TVIS10019942
Fusion event
HBV-LOC105370265 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr13
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
77289006/76714871 (Hg38)
End
77289254/76715119 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA13E
Target gene
LOC105370265
Nearest miRNA
hsa-mir-1297/Upstream/10496547; hsa-mir-1267/Downstream/982893;
Nearest TSS
ENST00000623511/Upstream/700370; ENST00000646457/Downstream/118720;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1077794, chr13-CpG: 195/Downstream/170068
Upstream sequence
TTTACATTTAGATATTGGCAGAGACAGGCCGAAACAGTTTCTTCCCATTTTTGTTTGCCCTATGTGTAGAATAGAATCTACCAAACTATGTTTTACCTTT
Downstream sequence
TTTTATTTTTTATAAAGGCAATAAACAGTGATTTTCTTGCAGCTGTGTAGGCCATTATAGCAAACAGTTGTCTTTTACTCAGCGCCCCAGAGAGAACCTA
Target sequence
TTTTTTctgtgataagagttatttcatacatgagtttattttgtcttcataaatacctatttgatatatgagaaaactgagtcttagaaaggttaagtaacttactcaataccacacagtaaatggtagagttaggatttaaccccaaatccaactccagaatcccagcccttaagaagtctgctattctgcccttcAGAATGATTTTCTTGAGAAGGTTCAAAAGAAGCTAAGGCGAAAGCAGCAAA
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
Curate