VISDB Viral Integration Site DataBase

VIS ID

TVIS10019943

Fusion event

HBV-AKAP6 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2013

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr14

Cytoband

q13.1

Reference genome

Start

End

33302380/32833174 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1257 ; hsa-mir-4687-3p ; hsa-mir-7974 ; hsa-mir-583 ; hsa-mir-1276 ; hsa-mir-4311 ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-7641 ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-4755-3p ; hsa-mir-4695-3p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-483-5p

Nearest miRNA

hsa-mir-208a/Upstream/1818136; hsa-mir-1185-1/Downstream/4119135;

Nearest TSS

Nearest CpG islands

None/Target, chr14-CpG: 35/Upstream/629169, chr14-CpG: 168/Downstream/99714

Upstream sequence

agactGCATTCCAAGGACCTGCTGCCAAGTCCTTCATAGCCACACAGCAGTTTAGAGAACCTGCTCCTCCCTTTACCCTACAATCCACAACAGCTCCAAA

Downstream sequence

ATTTattcagccattcagcaaacatttattaaatggctacctatgtgaggcactatatttggcattaggtatataaaggcaactaacacatggtatctgt

Target sequence

tcagatccattccaacctgACTGAATGTTAACAGACAGAATTCTTCACATTAAGGAACTGTCTTCATCATCATACATGTAGAAAAGAATCTGAACATTTAAGTGCGAAGTTTTCTCTAGAAATATATTCAAGATATGTTTATTCTATTATTGTAAATTTCAAACAATAAATAAATAAGAATCCATGACTTCCTTCAGTGGCCCAGTCCAGTGCCTAAGTCATCTGGAATCTTCTCCTTACATCGAATACAAACCT