Basic Information
VIS ID
TVIS10019944
Fusion event
HBV-chr21:q21.3 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
29725597/28353277 (Hg38)
End
29725705/28353385 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/1399234; hsa-mir-3197/Downstream/2021909;
Nearest TSS
ENST00000624081/Upstream/124610; ENST00000412526/Downstream/185933;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1209290, chr21-CpG: 29/Downstream/531718
Upstream sequence
CTCTATTTGCATGTACAAATATGGGTTTCAAGTACCCAATACAATTAAATTACACAAACACATATGCTAATATAATGTGTTGTAGTTGTCGAGTTTTTTT
Downstream sequence
cctaggtattttattctctttgaagcaattgtgaatgggaattgactcatgatttggctctctgtttgtctgttgttggtgtgtaagaatgcttgtgatt
Target sequence
CTCAGTAAAATATCAAGGATGAATGAGCTCATTAGTTCCACAGTAAGCAATTCTTCTCCCTCAAAGCAtcttattttaaaatactccacatcccttgtaagttggatt
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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