Basic Information
VIS ID
TVIS10019945
Fusion event
HBV-chr5:p15.33 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
4192829/4192716 (Hg38)
End
4192981/4192868 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-4277/Upstream/2483848; hsa-mir-10397/Downstream/2634985;
Nearest TSS
ENST00000502646/Upstream/57034; ENST00000503188/Downstream/247391;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/230318, chr5-CpG: 39/Downstream/673336
Upstream sequence
GGCCGTGCACATCCACCAGAAACACGCTGAATGGTGAATCCTGTCTTCGCCAGCTTATCCTCTCTGCCATCTCCTTCGCTGAAAGTTTGGGGTTCGGCCG
Downstream sequence
CACAGCATTCAACCACCTGCCAAGCAGTTTATTAGTCTCTCTAACCACCCAAAGTAATCCTCAAGGTTCCTTTTGAGTAAAATTCCCGGCATTGAATGAT
Target sequence
TGAGATGTCAGAATTTGTAATCAAATTGTATAATCAGAGAGCCAGATACAATTTCTATAGGCCCAATTATTGCCCATGCCTATTTTAAACATTATGAATATTCCTGGGAATTATTTTCATCCCATTGAAAAACTTTTGAGACATTAGCTCAC
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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