Basic Information
VIS ID
TVIS10019951
Fusion event
HBV-chr16:p11.2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31414820/31403499 (Hg38)
End
31414964/31403643 (Hg38)
Location type
Intronic
Target gene
ITGAD ; PRPF31
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-1225/Upstream/509514; hsa-mir-11401/Downstream/2759935;
Nearest TSS
ENST00000527434/Upstream/10164; ENST00000567308/Downstream/20299;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/31681, chr16-CpG: 86/Downstream/23927
Upstream sequence
TCCAGATGAGAGGACTGCAAATGATGTCTTTCCAGAATCAATCACATCTCAGTAGAGTCATCTTCCTTTCCTCCCCGACAGGACACAGCTATTTCATCAT
Downstream sequence
GTGTAAGCAACCCCGACCCCAGCCTGGCGATGTGACTGCCACCCCCACTTCCTAACCCTGGGTCAGCACAGCTCTTCTCAGAGGCTGAGGGAGGCTCCAG
Target sequence
TTTGCACTGATGCAGTACTCAAACCTCCTGAAGATCCACTTCACCTTCACCCAATTCCGGACCAGCCCGAGCCAGCAGAGCCTGGTGGATCCCATCGTCCAACTGAAAGGCCTGACGTTCACGGCCACGGGCATCCTGACAGTG
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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