Basic Information
VIS ID
TVIS10019953
Fusion event
HBV-chr16:p11.2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31402241/31390920 (Hg38)
End
31402508/31391187 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/496935; hsa-mir-11401/Downstream/2772391;
Nearest TSS
ENST00000527434/Upstream/19446; ENST00000444228/Downstream/2125;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/19102, chr16-CpG: 86/Downstream/36383
Nearby gene
ITGAX(-7923) ; ITGAD(+2303) ;
Upstream sequence
tgaggccaggagtttgagAGACCCTGTCTCTACAAAAAATTAAAATAAAAACAATAGTAACAGGCACTGAGCCCTGGGCCCTCCCCACTGGCCTTTGCAG
Downstream sequence
CGGCTCGGTTTCCTGCAAGGGCATCGTTAATGCATCACAATTAATTTCTTCTGTCCATTAAATGTCAGCTCTCAAGTAAATTGATGTAAAATTTTTGTAT
Target sequence
GGATATAGAAATGTGTAAAAGATGAGGTGTGGTGAAGATGGAGAAAATGAAGAGCTCTTTAAATTTCTGAATTATGAAGAATCACCAACAAATTATTTTGTGGTTCCAAATACAGGGAGAAGTTCACAGATCCACAGAACTGATGACAGGGTGCGGCCAGCCACAAACCTTTCAGCACAAGAGGGAGAAGGCTGCCGCTCCACTTTGCCTGGGCAGTCTTTGTAAGGCAGTAGATAAGTCAGCCTCGAAGTTAGC
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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