VISDB Viral Integration Site DataBase

VIS ID

TVIS10019955

Fusion event

HBV-KMT2B integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2013

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr19

Cytoband

q13.12

Reference genome

Start

End

36214173/35723271 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-7515 ; hsa-mir-302a-5p ; hsa-mir-3154 ; hsa-mir-6782-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-5692a ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-20b-5p ; hsa-mir-153-3p ; hsa-mir-1224-3p ; hsa-mir-1294 ; hsa-mir-1914-3p ; hsa-mir-214-3p ; hsa-mir-31-5p ; hsa-mir-3184-5p ; hsa-mir-3619-5p ; hsa-mir-3689d ; hsa-mir-423-5p ; hsa-mir-4316 ; hsa-mir-4426 ; hsa-mir-4440 ; hsa-mir-4459 ; hsa-mir-4647 ; hsa-mir-4662b ; hsa-mir-4688 ; hsa-mir-4722-5p ; hsa-mir-5194 ; hsa-mir-6085 ; hsa-mir-6165 ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6743-5p ; hsa-mir-6789-5p ; hsa-mir-6813-5p ; hsa-mir-6851-5p ; hsa-mir-761 ; hsa-mir-7704 ; hsa-mir-885-3p

Nearest miRNA

hsa-mir-10395/Upstream/377232; hsa-let-7e/Downstream/3686352;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/2835, chr19-CpG: 24/Downstream/455

Upstream sequence

CGTCACCACAGCAGATGCCTCCCCTGGAAAAAGCCCGGATTGCGGGCGTGGGTTCCTTGCCGCTGTCTGGGGTAGAGGAGAAGATGTTCAGCCTCCTCAA

Downstream sequence

TGTGTGAGTAGCTGGGGCGTGACCTCATTCCCGTGGTTGTTGGTCCCCTAGGCTTCCTACCTCACTCCTCTTCTGCCTGGCCAGAGCAGTGGGGTTGGCA

Target sequence

GAGCAACTTCATTTGGGGGCACCAGGAACCTGGCGCTGTGAGAAAGCGAGAGCCAGGTTGTGGGAAAGCAGGGAAGTGAGGTAGAAGCCTGGTGGCTTTGTGGCTCCATCCCCTCCTCCCTGCCTGCTGCAATAGATACATCATCGGCGTCCGAGACTGAGAGTGTCCCGTCACGGTCCCGGCGGGGAAAGGTGGAGGCAGCAGGCCCTGGGGGAGAATCAGAGCCCACAGGTTCTGGAGGGACCCTGGCCCACA