PRPF31 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10019959
Fusion event
HBV-PRPF31 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr14
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
23429865/22960656 (Hg38)
End
23430031/22960822 (Hg38)
Location type
Intronic
Target gene
PRPF31
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-383-3p
Nearest miRNA
hsa-mir-4707/Upstream/3627; hsa-mir-1185-1/Downstream/427774;
Nearest TSS
ENST00000550708/Upstream/3495; ENST00000557615/Downstream/14473;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/3408, chr14-CpG: 204/Downstream/19855
Upstream sequence
tactccctctttctcatggcaaccctgaagataatcaaggccagttactcatcatctcccaaccactgtttcctcaactgcccttcatatgtcatggttt
Downstream sequence
cattgaggtattttggcacacagtatttaaagtgtacaattcaatacattttgatataactatatatgtgtgaaaccatcaccaagatcaagatagtgaa
Target sequence
GTGCAGTGAAGTGCTGGGAAAAAAAGTTTATAATCAGACACCATCCGGTGTCCTTGAACAAGAAAGAATTGTAAGAAAGGACCTAGAATTCATTCATATtctctctctctctctccctctgtccttctctttccctctTTTTTGCCAGAAttttaaaaaacagctt
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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