Basic Information
VIS ID
TVIS10019960
Fusion event
HBV-chrX:p11.4 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chrX
Cytoband
p11.4
Reference genome
GRCh37/hg19
Start
38167314/38308061 (Hg38)
End
38167552/38308299 (Hg38)
Location type
Intronic
Target gene
RPGR ; SNORA31 ; SREBF2-AS1
miRNAs that regulate target gene
hsa-mir-375
Nearest miRNA
hsa-mir-23c/Upstream/284075; hsa-let-7f-2/Downstream/1352917;
Nearest TSS
ENST00000429181/Upstream/3230; ENST00000488812/Downstream/10691;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/51744, chrX-CpG: 57/Downstream/18870
Upstream sequence
aatactatcaccttggaagatagtgcttcaacatgtgatttggagggtacatgaacattcagttgatagcattctgcccctggggcccccaaattcatgc
Downstream sequence
GAGAGCAATCAATTTCTGGAAACATTATACTTAAGCTCAGAACAAAGTCCACAGAAAGTTAAATGTCTTTAAAACCACACGAAAATATCATCCTTAAGTG
Target sequence
CTGTAAAAATTATCTCTCCATGTTTTTTTCCCTGTATTACCAAGTTTTTCTCCTGTATTCCCCCATTCAATGTTGGCTGCCACAATCAGAAAGGAAATGCAAGGACACTTCTTTCTTGCATCTGTAGTAGAAATCTTAGTGGCAAAAAATAACTGTTCCAGGTCTGTCAAATAGATGCATCTCATAATTTAAAAAACTTTACTGGTGTGTGAGATCCGTAAGCTTGCAAAAATCTGGA
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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