VISDB Viral Integration Site DataBase

VIS ID

TVIS10019961

Fusion event

HBV-TMTC2 integration

Validated

No

Detection method

RNA-Seq

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2013

PubMed ID

Virus name

HBV

Reference genome

Chromosome

chr12

Cytoband

q21.31

Reference genome

Start

End

83256354/82862575 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-4470 ; hsa-mir-561-3p ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-6734-3p ; hsa-mir-6832-3p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251

Nearest miRNA

hsa-let-7i/Upstream/1703925; hsa-mir-1178/Downstream/3882493;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/174519, chr12-CpG: 17/Downstream/2048846

Upstream sequence

TCAGCAGATGCTCTGTACTTCTCATTCAGtcatttagttggcaaatatttattagccatctatacgagatgtgctgcaccaggcacagaggatacagaaa

Downstream sequence

TTATCTAGGTAATCTCTTTTTCTTAAAATTAAATTTTGTGACTCTGTTTCAATAAATAATATTGTTATATGGGAAAATTGGAGACATTGAGATTTTCCAG

Target sequence

AGCCTCATAACCACTTATTCAGTTACAGGTGGAAAATTTTAAAAATCTGAAAGTCAATGTAGCAATACTAATACTAACACAAGATAGTTTAGAAAAATGAAGCCCTTTTAGTTTGATGTTTTTAAAATTTCTCTAAAGATGATTACCTTGGTTTTGCTAAAGTTTATGTAGTTGGTTCCAAGATGTGCA