Basic Information
VIS ID
TVIS10019963
Fusion event
HBV-chr18:q22.1 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr18
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
65970225/68302988 (Hg38)
End
65970380/68303143 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA18C
Nearest miRNA
hsa-mir-1-2/Upstream/1221302; hsa-mir-548av/Downstream/4550178;
Nearest TSS
ENST00000575820/Upstream/38161; ENST00000577835/Downstream/123887;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/786252, chr18-CpG: 67/Downstream/411554
Upstream sequence
aaggcagctctctagggtgtcttttataagggcactaattccatctgacataatcacctgcaaaaggccccacttcctattgccttaggggttagaattt
Downstream sequence
TGCAAAAACAATCGCTTGAGATTACTGGAATGTTGTTTATTTTATGATAGTGAGAGAGCTAAGCcaaaactgcacaactacatggaaactgaacaacctg
Target sequence
TTTATTCTTGTCTTCACACTTAACATTCCTGTGTTTTCATTTATTTAATTACATGTAGTAGTGTTTAGACTTTGTATTAAATCATCatttataatattaaatcatcatttataatattaaatatatatataaaGGAGATTAGAGTGTTGGGACTT
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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