Basic Information
VIS ID
TVIS10019976
Fusion event
HBV-chr12:q12 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37/hg19
Start
38697937/38304135 (Hg38)
End
38698162/38304360 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/12430056; hsa-let-7i/Downstream/4019340;
Nearest TSS
ENST00000382841/Upstream/4085282; ENST00000553138/Downstream/12218;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/140244, chr12-CpG: 25/Downstream/12230
Upstream sequence
GCCATTCTCTTATACCCAATGGCTGAAGAAGCATTGGCAGCAGGAACAGGCTAGAACAGACAGAGGAAGTAAGTGAGGCCATGCTCTCTCTTACTCCCCA
Downstream sequence
tggttatcatattagacagcataaaatacattttaattattgtggaaagttgtgttTTAAAATTTTTATAGAGAATTATGTACCTTTAGACAATGTCTAA
Target sequence
aaatacaaaaattagccaggcatggtggcacaggcctgtagtcccagctactcgagaggccgaggcaaaagaattgcttaaacccagaaggcagaagttgcagtgagccgagatggagccattgcactccagcctgggcaacaaagcgagactccatctcaaaaaaaaattaattaattaatttaattaaagtctctgttcaactaccctagtcgcatgtggctg
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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