Basic Information
VIS ID
TVIS10019977
Fusion event
HBV-chr2:q37.3 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
239062834/238154193 (Hg38)
End
239063147/238154506 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA2J
Nearest miRNA
hsa-mir-10b/Upstream/643205; hsa-mir-149/Downstream/914311;
Nearest TSS
ENST00000437798/Upstream/15471; ENST00000486834/Downstream/4476;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/3184, chr2-CpG: 51/Downstream/4430
Nearby gene
KLHL30(-1287) ; ERFE(+4815) ;
Upstream sequence
AAAGCAAGATCTGCCCACTCTCAAAGTAAATGTTTGACTCTCAGAGAAGCCTCCTAAGCTCAAGAGGAAATTTATATGTCAACAGAGTGGTAATGATGCC
Downstream sequence
ccaaataaacctcttttctttgtaaattacccagcctcacattttcctttatagcaagaaaacagaAGGATACAGGCCACTACTCCAGTTGGTTGGGCCA
Target sequence
gcttggagatctgtcccctccgaatctcatgttgagtctgttgagtctgatcgctggtgttggagttgggcctggtgggaggcgtttagatcatgggggcggatccctcaggcatggcatggtgcagtaacgctggtgcgttcacggagagctgatcgttaaagagcctgacacctcccctgctctcccttgctccctcactgtgtgacacacctgctccccttcccctgccaccgtgagtggaagcttcctgag
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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