Basic Information
VIS ID
TVIS10019985
Fusion event
HBV-chr19:q13.42 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
53830648/53327395 (Hg38)
End
53830881/53327628 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA19A
Nearest miRNA
hsa-let-7e/Upstream/1045502; hsa-mir-10394/Downstream/339051;
Nearest TSS
ENST00000633603/Upstream/35769; ENST00000595091/Downstream/6118;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/18637, chr19-CpG: 17/Downstream/1490
Nearby gene
ZNF845(+6324) ;
Upstream sequence
ACCCCACACTTGGGTGACATGCACCAAGAGCCTAGGAGAGAGGGAGCCAAGTCAGGTGCTCAGGGGTTAGGTGGCAAGTGGGCTGGAGTGCTAGGTCCTA
Downstream sequence
aagcatagggtctcaagggccccgttacagaattttcaggagttaaataccatctagaggattccagtggttacttggtgcatgccctatgtaaataaaa
Target sequence
ATGAATTCAGGATCCAAGTTAAATTTGTGAATATAGGAATGGAATATAGGCTGCTGGGGAATAGCAATTTCTGGTGGGGAATTGAGACCGCAACACACCACAGTtgttaccagtggagggtgtccaggttcttcgtgtcttgaacaaagaattggacaaaatgcataaattaaggaaggaataaatggatttattgaaaatgaaagtacactccacagtgtgggagctggccc
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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